Congenital Infantile Fibrosarcoma: A Clinical Mimicker and Histopathological Surprise

Preeti Sharma, SufianZaheer, Amit Kumar Yadav


Congenital infantile fibrosarcoma is defined as fibrosarcoma in children below 2 years of age. It is a rare soft-tissue malignancy with only 300 cases reported in the world literature. Herein is presented a case of a 10-month-old infant with a soft-tissue swelling over his right sole. The swelling was present since birth with sudden increase in size and change in color in the overlying skin. With a clinical diagnosis of a vascular tumor, excision was performed. Microscopy showed a cellular tumor with spindle-shaped cells arranged predominantly in sheets. Atypical mitosis was seen. Scattered lymphocytes were also seen. The tumor cells were positive for vimentin. A final diagnosis of congenital infantile fibrosarcoma was made. Clinically, it can be confused with a tumor of vascular origin. Compared to its adult counterpart, the clinical course of infantile fibrosarcoma is a favorable one. It is intended to describe this case due to its rarity and to increase awareness about this entity amongst clinicians and pathologists to prevent misdiagnosis.


Aggressive, Congenital, Infantile fibrosarcoma.

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