Correlation between Retinal Nerve Fiber Layer Thickness Measured with Spectral Domain Optical Coherence Tomography and Visual Field in Patients of Primary Open Angle Glaucoma

Diksha Prakash, M K Singh, P Bhushan


Aim: To study the correlation between retinal nerve fiber layer (RNFL) thickness measured with spectral domain optical coherence tomography (SD-OCT) and visual field (VF) in patients of primary open angle glaucoma (POAG).

Materials and Methods: A total of 60 patients of POAG and 60 controls were studied for a period of one year from July, 2011 to June, 2012 in the Department of Ophthalmology, Institute of Medical Sciences, BHU. All the patients and controls underwent visual field analysis by standard automated perimetry using SITA standard 30-2 program and optic disc imaging by Cirrus SD-OCT. The relationship between RNFL thickness and VF sensitivity, expressed as mean deviation (MD) and pattern standard deviation (PSD) were evaluated. The association between RNFL/VF was described by Spearman’s rho correlation coefficients.

Results: The correlation of RNFL and the VF parameters MD and PSD in normal eyes was not significant. In POAG eyes, RNFL and both MD (R=0.925) and PSD (R=-0.879) correlated significantly.

Conclusion: The study demonstrated that the correlation between RNFL and visual field parameters MD and PSD in normal eyes was not significant. In POAG eyes, RNFL and both MD and PSD correlated significantly with P <0.001.


Retinal nerve fibre layer (RNFL) thickness, Mean deviation (MD), Pattern standard deviation (PSD), Primary open angle glaucoma (POAG).

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