Clinical Profile of Dengue Fever at SCB Medical College and Hospital, Cuttack, Odisha

Sasmita Kumari Bisoyi, Tapas Ranjan Behera, Nupur Patnaik, Arun Pradhan

Abstract


Background: India is one of the seven identified countries in the South-East Asia region regularly reporting dengue fever outbreaks and epidemics and has transformed into a major niche for dengue infection with more new areas being struck by dengue epidemics like Odisha. The present study was aimed to assess clinical profile and current status of dengue cases admitted in Dengue ward of SCB Medical College hospital, Cuttack, Odisha.

Methods: It was a cross sectional prospective observational hospital-based study between July to September 2016 in the Dengue ward of SCB Medical College Hospital, Cuttack, Odisha. Of 3600 dengue patients admitted at this hospital during the study period, a total of 720 cases were selected by systemic random sampling method. (20% of daily 40 new dengue cases). The clinical manifestations and laboratory findings of each group of illness were compared using Chi-square test.

Results: Out of 720 dengue patients, 82.5% were Non-severe Dengue and only 17.5% were Severe Dengue. The Mean age of patients was 36±14.6 years with a male to female ratio of 4:4.1. However, bleeding manifestations like epistaxis, melena were seen in in 15.4% cases especially in severe dengue cases. Rash was present in 17.5% cases. 64 severe dengue cases had TPC less than 50, 000. Among different treatment protocols given to all these dengue patients, 55.7% of non-severe dengue cases were treated with paracetamol and antibiotics, whereas 38.9% of severe dengue cases were treated with paracetamol, antibiotics and platelet infusion. Only 5.7% of non-severe dengue cases were referred to ICU, whereas 50% of severe dengue cases were referred to ICU.

Conclusion: The present study highlights the importance of dengue fever to the clinician in the area of epidemiology, its varied manifestations, complications, and outcome of the disease with no specific antiviral therapy or vaccination available in our country, mortality from dengue fever can only be prevented by its early diagnosis and timely management.


Keywords


Clinical Profile of Dengue patients, Dengue, Dengue fever

Full Text:

PDF

References


Sunderlal AP. Textbook of Community Medicine. 5th

edition, CBS Publishers, 2017. p.497.

WHO. Dengue and dengue haemorrhagic fever.

Factsheet no. 117, World Health Organization, Geneva,

Switzerland, 2008. Available from: http://www.who.

int/mediacentre/factsheets/fs117/en/.

Special Programme for Research, Training in Tropical

Diseases and World Health Organization. Dengue:

Guidelines for Diagnosis, Treatment, Prevention

and Control, World Health Organization, Geneva,

Switzerland, 2009. Available from: https://www.who.

int/tdr/publications/documents/dengue-diagnosis.pdf.

Gupta N, Srivastava S, Jain A et al. Dengue in India.

Indian Journal of Medical Research 2012; 136(3): 373-

Das B, Das M, Dwibedi B et al. Molecular investigations

of dengue virus during outbreaks in Orissa state,

Eastern India from 2010 to 2011. Infection Genetics

and Evolution 2013; 16: 401-410.

Park K. Park’s Textbook of Preventive and Social

Medicine. 24rd edition, M/s Banarasi Das Bhanot

Publication, Jabalpur. 2017: 261.

Longo DL, Fauci A, Kasper DL et al. Harrison’s Principles

of Internal Medicine. 18th edition, McGraw Hill

Publication, 2011. p.1621-22.

Ministry of Health and Family Welfare, Government

of India. National Vector Borne Disease Control

Programme. Dengue/dengue haemorrhagic fever,

Available from: http://www.nhp.gov.in/nvbdcp.

Last accessed on 16 September 2017.

Ministry of Health and Family Welfare, Government of

India. Directorate General of Health Services. Guidelines

for Clinical Management of Dengue Fever, Dengue

Haemorrhagic and Dengue shock syndrome. 2008: 1-8.

Rigau-P´erez JG, Clark GG, Gubler DJ et al. Dengue

and dengue haemorrhagic fever. The Lancet 1998;

: 971-977.

World Health Organization. WHO report on

global surveillance of Epidemic prone infectious

diseases. Available from: http://apps.who .int/

iris/bitstream/10665/66485/1/WHO CDS CSR ISR

1.pdf.

Padhi S, Dash M, Panda P et al. A three-year retrospective

study on the increasing trend in seroprevalence of

dengue infection from southern Odisha, India. Indian

J Med Res 2014; 140: 660-664.

Mishra B, Turuk J, Sahu SJ et al. Co-circulation of all

four dengue virus serotypes: First report from Odisha.

Indian J Med Microbiol 2017; 35(2): 293-295.

Mishra S, Ramanathan R, Agarwal SK. Clinical profile

of dengue fever in children: A Study from Southern

Odisha, India. Scientifica 2016; Article ID 6391594: 1-6.

Brinda J, Selvaraj S, Ponnaian JC et al. Clinical profile

of dengue fever in Kanyakumari Government Medical

College - A study from Kanyakumari, India. J Evid Based

Med Health 2017; 4(1): 43-45.

Sharma GK, Bhatt D, Garg GK et al. A prospectiveseroepidemiologic study on dengue in children in

South-eastern Rajasthan, India. Int J Pediatr Res 2016;

: 726-31.

Gupta E, Dar L, Kapoor G et al. The changing

epidemiology of dengue in Delhi, India. Virology Journal

, 3: 92.

Bhardwaj LM, Borthakur S, Bhattacharyya PC. Clinicoepidemiological

study of dengue cases in a tertiary

care hospital, Guwahati, Assam. Int J Adv Med 2017;

(6): 1605-1612.

Kumar A, Rao CR, Pandit V et al. Clinical Manifestations

and Trend of Dengue Cases Admitted in a Tertiary Care

Hospital, Udupi District, Karnataka. Indian J Community

Medicine 2010; 35(3): 386-90.


Refbacks

  • There are currently no refbacks.


Copyright (c) 2018 Journal of Communicable Diseases (P-ISSN: 0019-5138 & E-ISSN: 2581-351X)

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.