Journal of Communicable Diseases

Debasish Chattopadhya
Department of Microbiology, Faculty of Health and Medical Sciences, SGT University, Gurgaon - 122505
India

 

    

 

RESUME

 

 

 

Name                                                  Debasish Chattopadhya

 

 

Date of birth                                      2^nd August, 1951

 

 

Gender                                               Male

 

 

 Immediate past designation            Additional Director (Microbiology) & Head,

                                                            Center for AIDS and Related Diseases

                                                            National Centre for Disease Control (Formerly NICD),

                                                            Delhi, INDIA

      

 

 

Corresponding Address                   A2/19,

Paschim Vihar

                                                            New Delhi-110063, INDIA

 

 

Contact details                      

                                                            Tel No (Residence):    +91-011-43738821

                                                            Mobile:                        +91-9811256697

                                                            E-mail:                      debasishchattopadhya@yahoo.com 

                                                                                                          dchattopadhya27@gmail.com

 

Qualifications                         MD (Medical Microbiology)

                                                            MRC Path (UK)

                                                            FRC Path (UK)

 

 

Proficiency in Languages                 English; French (Certificate de Francais Elementaire)

 

 

Personal habit                                    Nonsmoker                 

 

 
Membership of Academic Associations:

 

 

• Indian Association of Medical Microbiologists          (Life Member since 1984)
• New York Academy of Sciences, USA                     (2001)
• American Society of Microbiologists                         (1992–1995)
• Indian Society of Blood Transfusion                          (Life member since 1990)

 

 

Research Experience: More than 30 years

 

Main Areas of Work: AIDS; STD; Leprosy and other Tropical Diseases

 

 

Positions Held:

 

Designation

 

Duration

Organisation

Additional Director (Microbiology), Center for AIDS and Related Diseases

04.08.2009 to 31.08.13

National Centre for Disease Control (Formerly NICD), Government of India, Delhi

 

Assistant Director General (International Food), National Codex Contact Point, India

 

18.10.2006 to 03.08.2009

Ministry of Health & Family Welfare, Government of India, New Delhi.

 

Assistant Director General (Prevention of Food Adulteration)

 

10.02.2005 to 17.10.2006

 

Ministry of Health & Family Welfare, Government of India, New Delhi.

Joint Director, Division of AIDS

Office in charge, AIDS Reference Laboratory

 

27.09.1993 to 09.02.2005

 

National Institute of Communicable Diseases (NICD), Government of India, Delhi

Assistant Director,

Division of Microbiology & AIDS

27.09.1985 to 26.09.1993

 

National Institute of Communicable Diseases (NICD), Government of India, Delhi

 

Research Officer

 

01.07.1984 to 25.09.1985

 

WHO–ICMR Advanced Center for Research in the field of Rheumatic Fever/Rheumatic Heart Diseases, New Delhi.

 

Post Graduate Student & Resident

 

31.05.1982 to 15.06.1984

 

Lady Hardinge Medical College, University of Delhi, New Delhi

 

Demonstrator in Microbiology

01.07.1978 to 31.05.1982

All India Institute of Hygiene & Public Health, Directorate General of Health Services, Government of India, Kolkata.

 

 

 

Contribution in development of National Programs

 

Blood Safety Program:

 

• Carried out studies for 7 years on the risk of transfusion mediated infections associated with remunerated blood donation system in India supported by publications (13 in international journals) helped Government of India to legalize abolition of remunerated blood donation system in the country.
• Undertook for the first time in India a  country level WHO sponsored survey of blood banks regarding testing status for transfusion mediated infections (TTIs). The report has been published by WHO.
• Completed a project on ‘Assessment of magnitude of Transfusion mediated Cytomegalovirus (CMV) infection, a molecular based study’.

 

Other National Programmes:

 

• Development of quality control of HIV testing in India.
• Participation in the international quality control program in collaboration with WHO (Conducted by NRL, Australia)
• Establishment of quality control program for CD4 / CD8 counting in blood.
• Participation in WHO sponsored evaluation of voluntary counseling and testing centers  in various states of India.
• Assessment of laboratory parameters for monitoring antiretroviral therapy  for AIDS patients i.e peripheral  CD4/CD8 counts, plasma  viral load estimation  and diagnosis of opportunistic infections.
• Evaluation of National HIV testing policy : Validation of  the efficacy of cost effective alternative strategy for HIV testing (i.e. multiple screening tests in comparison to conventional western blot) for past decade ever since the concept was conceived in India.

 

Temporary adviser appointed by WHO/UNAIDS :

 

• Intercountry training on Quality Management Training in Blood Transfusion Services in South East Asia Region held in NIB, NOIDA, India 5 – 8 February, 2001.
• Intercountry meeting for reviewing the curriculum and training material for QMT courses, held in New Delhi, India 31^st May – 1^st June, 2001.
• Training course for Laboratory Personnel in Quality Assurance in Blood Serology and Transfusion Transmissible Infections held in Katmandu, Nepal 02–07 July, 2001.
• Quality Management training in Blood Transfusion Services in Indonesia, held in Jakarta, Indonesia 6–24 August, 2001.
• Sub Regional training course on Quality Management in Blood Transfusion Services for Bangladesh, Maldives and Bhutan held in Chittagong, Bangladesh, 1–18 September, 2002.

 

Manpower development:      Expert Faculty in Training Courses/Workshops (involving theoretical lectures and bench level laboratory exercises): A total of 83 medical and 180 supportive laboratory personnel have been trained over past 6 years

 

 

 

 

Academic award :

 

Research Award in the name of Smt. Sushila Rani and Shaheed Madhusudan Bhagat for research in “Rheumatoid and Allied Diseases, especially for the relief of pain” in the year 1984, Lady Hardinge Medical College, New Delhi.

 

 

Training abroad:

 

• USAID Sponsored Training in the field of AIDS at Retrovirus Laboratory, State Department of Health and Mental Hygiene, Baltimore, MD, USA, 1992.
• WHO sponsored inter-country training on “Promotion of cost effective approached in the laboratory diagnosis of HIV infections held in Jakarta, Indonesia, October, 1992.
• WHO Sponsored Training on diagnosis of HIV associated opportunistic infections, held in Bangkok, Thailand, 2003.

 

 

Academic Recognitions :

 

• Examiner for MD/ M. Phil/ Ph. D/MPH candidates in University of Delhi and Jawaharlal Nehru University.
• Guest speaker on various topics related to Virology, Immunology, AIDS in scientific meetings all over the country.
• Member, Expert Committee, Indian Council of Medical Research, CSIR

 

Expert reviewer for journals:

 

• HIV Medicine
• Indian Journal of Medical Research
• Journal of Communicable Diseases

 

Guide/Co-Guide for research students:      5 MD and 4 Ph.D students enrolled in University of Delhi and other Universities on topics related to HIV/AIDS and Transfusion Transmitted Infections (TTI)

 

Publications (vide annexure)

 

Area

International

Journals

National

Journals (indexed)

Total

HIV / AIDS

17

4

21

STD

6

-

6

Tropical Diseases

(TB, Leprosy, Kala azar, Malaria)

 

16

 

1

 

17

Zoonotic dermatophytes

4

--

4

Respiratory infections

5

3

8

Total

48

8

56

 

 

 

PUBLICATIONS

               (Publication in International Journals are marked by * sign)

 

1.       HIV/AIDS

 

 

 

*1        Behavioral risk factors for acquisition of Human Immunodeficiency Virus infection and knowledge about AIDS among male professional blood donors in Delhi.  Chattopadhya D, Riley LW and Kumari S. 

Bull WHO  1991 ;  69 : 319-323.

2          Limited evidence of Human Immunodeficiency Virus type 2 infection in sera of blood donors showing reactive ELISA but negative or inderminate Western Blot reactivity for HIV-1 infection. 

            Chattopadhya D, Kumari S and Verghese T.

             J  Com  Dis  1991 ; 23 : 206-207.

*3        Role of transfusion  mediated viral infections on the lymphocyte subset profile in  multitransfused children. 

            Yadav S, Chattopadhya D, Prakash C, Kumari S and Verghese T. 

            J Trop Ped  1993 ; 39 : 243-250.

4          Acquired Immunodeficiency Syndrome (AIDS) in multitransfused children with Thalassemia. 

            Sen S, Mishra NM, Giri T, Pande I, Khare SD, Kumar A, Choudhury VP, Chattopadhya D, Kumari S and Malaviya AN. 

            Ind Ped  1993 ; 30 : 455-460.

*5        Aspergillus fumigatus specific antibodies in multitransfused children with Human Immunodeficiency Virus (HIV) infection in relation to serum levels of Interleukin-2, Gamma Interferon and Tumour Necrosis Factor. 

            Bhatnagar PK, Chattopadhya D, Sharma GL, Sen S, Madan T and Sharma PU. 

            J Trop Ped 1996 ; 42 : 85-90.

*6        Does Aspergillus fumigatus play a role  in the disease progression from HIV infection  to AIDS? [Letter].

            Bhatnagar PK, Chattopadhya D and Sharma PU

Serodiag Immunother1996;8:61.

*7        Lack of evidence  of HIV-2 infection among  multitransfused Thalassemic children in the city of New Delhi [Letter].

            Chattopadhya D, Aggarwal R, Sen S, Kumari S and Verghese T.

            J Trop Ped, 1996, 42: 116-117

 8         HIV-2 prevalence in Uttar Pradesh. 

            Kulshrestha R, Mathur A, Chattopadhya D and Chaturvedi UC. 

            Ind J Med Res  1996 ; 103 : 131-133.

*9        Profile of antigen specific antibody response detectable by western blot in relation to diagnostic criteria for Human Immunodeficiency Virus Type - 1 (HIV-1) infection.  Chattopadhya D, Aggarwal RK and Kumari S.

            Clin Diag Virol 1997 ; 7 : 35-42.

*10      Sexually Transmitted Disease (STD) markers in multitransfused children in relation to Human Immunodeficiency Virus Type -1 (HIV-1) infection-impact of STD markers in blood donors. 

            Chattopadhya D, Aggarwal R, Prakash C, Sen S and Kumari S. 

            J Trop Ped  1997 ; 43 : 178-181.

*11      Analysis of HIV seropositive thalassemic children for antibodies specific to Aspergillus fumigatus by luminescent immunoassay. 

            Sharma GL, Bhatnagar PK,  Chattopadhya D and Sharma PU. 

            J Clin Lab Anal 1997 ; 11 : 343-345.

 

*12      Prevalence of transfusion associated infections in multitransfused children in relation to mandatory screening of Human Immunodeficiency Virus (HIV) infection in donated blood. 

            Aggarwal V, Prakash C, Yadav S and Chattopadhya D. 

            South East Asian J Trop Med Publ Hlth 1997 ; 28 : 699 - 706.

*13      Evaluation of epidemiological and serological predictors of human immunodeficiency virus type - 1 (HIV-1) infection among high risk professional blood donors with western blot indeterminate results. 

            Chattopadhya D, Aggarwal RK, Baveja UK, Doda V and Kumari S.

             Clin Diag Virol, 1998 ; 11 : 39 - 49.

*14      Disease progression markers during asymptomatic  phase of HIV-1 infected children with unimpaired CD4+ cell values : Evaluation of repeat CD4+cell evaluation vs other immunological parameters.

            Chattopadhya D, Baveja UK, Bose M, and  Kumar A.

            J Trop Ped, 2002;48:340-347.

*15      Evaluation of immune status against diphtheria and tetanus towards prediction of bacterial infections in HIV-1 infected  children  vaccinated  with at least  primary course of  DPT vaccination. 

Chattopadhya D, Grover SS, Sharma M, Ichhpujani RL and Baveja UK.

Annal  Trop Ped 2003 ; 23 : 279-292.

*16      Oropharyngeal carriage of Candida species in HIV-infected patients in India. 

Gugnani H.C., Becker K., Fegeler W., Basu S., Chattopadhya D., Baveja U., Satyanarayana S., Kalghatgi T., and Murlidhar A.

Mycoses 2003 ; 46 : 299-306.

17        A cross sectional serological study of the co-infection of Hepatitis B virus, Hepatitis C virus and Human Immunodeficiency Virus amongst  a cohort  of IDUs  at Delhi.

Baveja UK, Chattopadhya D., Khera R., and Joshi PL.

Ind J Med. Microbiol 2003 ;  21 : 280-283.

18        Pediatric HIV Infection.

            Sehgal R, Baveja UK, Chattopadhya D, Chandra J and Lal S.

Ind J Pediat, 2005; 72: 925-930

*19      Role of HCV coinfection towards disease progression and survival in HIV-I Infected children: A follow-up study of 10 years.

            Shivraj SO, Chattopadhya D, Grover G, Kumar A, Baveja UK

            J Trop Ped, 2006;52:206-211

*20      Genomic Diversity in the Regulatory nef Gene Sequences in Indian Isolates of HIV Type 1: Emergence of a Distinct Subclade and Predicted Implications.

            Kumar M, Jain S, Pasha ST, Chattopadhya D, Lal S, Rai A

            AIDS Res Hum Retro 2006; 22: 1206-1219

*21      Nonparametric Estimation of the Incubation Period of AIDS with Left Truncation and Right Censoring

            Shivraj SO, Chattopadhya D and Grover G

            J Data Sci 2007; 5: 289-296.

*22        Hepatitis E virus infection and fulminant hepatic failure during pregnancy

Nishat J, Das B.C, Husain, S.A, Baweja U.K, Chattopadhya D, Gupta R.K, Sardana S, and Kar P.

J Gastroent Hepatol 2007; 22: 676-682.

 

2.       Sexually Transmitted Diseases

 

 

 

*1        Bleeding ectopy as an indicator for genital tract infection (Letter). 

            Singh V, Sehgal A, Gupta MM, Satyanarayan L, Parashari A, Sodhani P and Chattopadhya D. 

            Genito Urin  Med  1994 ; 70 : 424.

*2        Clinical presentation of gynaecologic infections among Indian women. 

            Singh V, Sehgal A, Satyanarayan L, Gupta MM, Parashari A and Chattopadhya D.  Obst Gynae 1995 ;  85 : 215-219.

*3        Association between reproductive tract infections and cervical inflammatory epithelial chages. 

            Singh S., Gupta MM, Satyanarayana L, Parashari A, Sehgal A, Chattopadhya D and Sodhani P. 

            Sex Trans Dis  1995 ; 22 : 25-30.

*4        Significance of inflammatory cervical smears. 

            Parashari A, Singh V, Gupta MM, Satyanarayan L, Chattopadhya D, Sodhani P and Sehgal A. 

            Acta Pathol Microbiol Immuno Scand  1995 ; 103 : 273-278.

*5        Mutagenicity of endocervical mucus associated with genital tract infections. 

            Parashari A, Singh V, Gupta MM, Satyanarayana L, Chattopadhya D, and Sehgal A.  Cancer Detect Prev  1996 ; 20 : 45-49.

*6        Coloscopy as a tool for detection  for human papilloma virus infection of uterine certix in the settings of high prevalence of gynaecological infections.

Singh V, Parashari A, Sodhani P, Chattopadhya D, Satyanarayana L, Gupta MM, and Sehgal A Singapore Med Journal 1996;37:588-590.

 

3.       Tropical Diseases

 

            Leprosy

 

*1        A study on nutrition, growth and development of a high risk  group of children of urban leprosy patients. 

            Saha K, Rao KN, Chattopadhya D, Lakshmi V, Gadi S and Duttabanic ND. 

            Eur J Clin Nutr 1990 ; 44 : 471-479.

*2        Sexually transmitted diseases in leprosy patients in north and north-eastern India.  A futile search for Human Immunodeficiency Virus anitbody. 

            Saha K, Chattopadhya D, Dash K, Saha U, Tyagi PK, Gupta MM, Parashari A and Sharma AK. 

            Int J Lepr 1990 ; 58 : 660-665.

*3        Nutritional status of children of urban leprosy patients staying at preventoria based on biochemical parameters. 

            Chattopadhya D, Saha K, Chakraborty AK, Rao KN, Patil SK, Sharma A and Dusaj IS. 

            Eur J Clin Nut 1992 ; 46 : 885-895.

*4        Delayed clearance of Circulating Immune Complexes in mice following administration of Antileprosy Drugs. 

            Kashyap A, Saha K, Sahu A, Chakraborty AK and Chattopadhya D. 

            Int J Lepr  1992 ;  60 : 404-409.

*5        Tumour necrosis factor : status in reactions in leprosy before and after treatment.  Sehgal VN, Bhattacharya SN, Chattopadhya D and Saha K.

            Int J Dermat  1993 ; 32 : 436-439.

*6        Prevalence of HIV infection and high risk characteristics among leprosy patients of South India ; a case-control study. 

            Sekar B, Jayasheela M, Chattopadhya D, Anandan D, Rathinavel L, Vasanthi B, Subramanian M and Rao PS. 

            Int J Lepr  1994 ; 62 : 527-531.

*7        An eight years field trial on antileprosy vaccines among high-risk household contacts in the Calcutta Metropolis. 

            Chaudhury S, Hazra SK, Saha B, Majumdar B, Biswas PC, Chattopadhya D and       Saha K.

             Int J Lepr 1994 ; 62 : 389-394.

*8        Enhanced Response of serum IgG class of anti PGL-1 antibodies in Leprosy patient during onset and following clinical remission of type 1 and type 2 reactions. 

            Saha K, Chattopadhya D, Kashyup A, Agarwal U and Chakraborty AK. 

            Int J Lepr  1995 ; 63 : 105-109.

*9        Biometals in the skin and sera of leprosy patients and their correlation to trace elements contents of M.leprae and histological types of the diseases ; a comparative study with cutaneous tuberculosis. 

            Jain A, Mukherjee A, Chattopadhya D and Saha K. 

            Int J Lepr  1995 ; 63 : 249-258.

 

*10      Immunotherapy of lepromin-negative borderline leprosy patients with low-dose convit vaccine as an adjunct to multidrug therapy : a six year follow up study in Calcutta.  Chaudhury S, Hazra SK, Mukherjee A, Saha B, Majumdar V, Chattopadhya D and Saha K. 

            Int J Lepr 1997 ; 1 : 56-62.

*11      Why relapse ocurs in PB Leprosy patients after adequate MDT despite they are Mitsuda reactive : lessons from Convit’s  experiment on bacteria-clearing capacity of Lepromin-induced granuloma. 

            Chaudhury S, Hazra SK, Mukherjee A, Saha B, Majumdar V, Chattopadhya D and Saha K. 

            Int J Lepr  1998 ; 66 : 182-188.

*12      Malaria, Leprosy and Dapsone.

            Saha K, Kapoor L,Arora V M,Chattopadhya D

            South East Asian J Trop Med Pub Health 2003; 34:501-504

 

Other Tropical Diseases

 

13        Antimalarial antibody in relation to seroreactivity for HIV infection in sera from blood donros. 

            Chattopahdya D, Kumari S, Chatterjee R and Verghese T. 

            J Com Dis 1991 ; 23 : 195-198.

*14      Blood bone marrow and splenic lymphocytes subset profile in India visceral leishmaniasis. 

            Rohtagi A, Agarwal SK, Bose M, Chattopadhya D and Saha K. 

            Trans Roy Soc Med Hyg 1996 ; 90 : 431-434.

*15      Concomitant Kala azar, Malaria and Progressive  Unstable Indeterminant  Leprosy in an eight year  old India Child

            Saha K. Chattopadhya D and Kulpati DD.

            J Trop Pediatr. 1998; 44:247-8

 

*16      Nitric oxide dependent killing of Mycobacterium tuberculosis by human mononuclear phagocytes from patients with active tuberculosis.

            Bose M, Farnia P, Sharma S, Chattopadhya D, Saha K.

            Int J Immunopathol Pharmacol 1999 ; 12 : 69-79.

*17      The Use of immunomodulators as an adjunct to antituberculosis chemotherapy in nonresponsive patients with osteoarticular tuberculosis.

            Arora A, Nadkarmi B, Dev G, Chattopadhya D, Jain AK, Tuli SM, Kumar S

            J Bone Joint Surg [Br] 2006; 88:264-269

 

4.       Zoonotic Dermatophytes of Public Health Importance

 

*1        Some epidemiological aspects of zoophilic dermatophytosis.

            Chatterjee A, Chattopadhya D, Bhattacharya D, Dutta AK and Sengupta D N.

            Int J Zoonosis 1980 ; 7 : 19-33.

 

*2        An unusual association of Trichophyton mentagrophytes and Demodex canis in a mongrel dog with multiple kerions.  

            Chatterjee A, Chattopadhya D, Sengupta DN, Chakrabarti A.

            Ann Trop Med Parasit 1980 ; 74 : 101-102.

*3        Isolation of dermatophytes from dung. 

            Chatterjee A, Chakrabarti A, Chattopadhya D and Sengupta DN.

            Vet Rec  1980 ; 107 : 399.

*4        Isolation of dermatophytes from rural and urban soil samples in premises of infected and non infected animals. 

            Chatterjee A, Chattopadhya D, Chatterjee D and Sengupta DN. 

            Int J Zoonosis  1983 ; 10 : 20-27.

 

5. Respiratory Infections

           

1.         Oxine blood agar slides for rapid identification of beta haemolytic streptococci at community level. 

            Prakash K and Chattopadhya D. 

            Ind J Med Microbiol 1985 ; 3 : 109-114.

2.         Group A streptococci resistant to Erythromycin and Lincomycin. 

            Prakash K and Chattopadhya D. 

            Ind J Med Res 1988 ; 3  : 391-394.

3.         Rapid diagnostic techniques in the etiological diagnosis of lower respiratory tract infections in children. 

            Chatterjee R, Sutaone B, Chattopadhya D, Ichhpujani RL, Joshi PR, Kumari S, Chopra K and Sehgal S.

            J Com Dis 1988 ; 20 : 226-231.

*4.       Lower respiratory tract infection in hospitalised children due to Respiratory Syncytial (RS) virus during a suspected epidemic period of RS virus in Delhi. 

            Chattopadhya D, Chatterjee R, Anand VK, Kumari S and Patwari AK. 

            J Trop Ped  1992 ; 38 : 68-73.

*5.       Aetiology of pneumonia in hospitalised children. 

            Patwari AK, Bisht S, Srinivasan A, Deb M and Chattopadhya D. 

            J Trop Ped 1996 ; 42 : 15-20.

*6.       Association of the PIM3 allele of the alpha-1-antitrypsin gene with chronic obstructive pulmonary disease.

            Gupta J, Bhadoria DP, Lal MK, Kukreti R, Chattopadhya D, Gupta VK, Dabur R,      Yadav V, Chillar AK, Sharma GL.

            Clin Biochem 2005; 38: 489-491

*7.       Phenotypic and genotypic detection of ESBL mediated cephalosporin resistance in Klebsiella pneumoniae: emergence of high resistance against cefepime, the fourth generation cephalosporin.

            Grover SS, Sharma M, Chattopadhya D, Kapoor H, Pasha ST, Singh G

            J Infect 2006; 53:279-288.

*8.       T Lymphocyte subset profile and serum alpha-1-anti-typsin in pathogenesis of chronic obstructive pulmonary disease.

            Gupta J, Chattopadhya D, Bhadoria DP, Qadar Pasha MA, Gupta V, Kumar M, Dabur R, Yadav V and Sharma GL

            Clin Exp Immunol 2007;149:463 -469.

 

***

 

A Verghese
Department of Microbiology, National Center for Disease Control, 22,Sham NathMarg, Delhi – 110054,INDIA

S Broor

Department of Microbiology,

Faculty of Health and Medical Sciences,

SGT University,

Gurgaon – 122505, INDIA