Status of Bone Mineral Density in Patients with Hyperthyroidism

Dr. Dinesh K Dhanwal; Vivek Dixit; R K Marwah

Keywords Acute-phase reactants, Erythrocyte sedimentation rate, C-reactive protein, Fibrinogen, Ferritin, Procalcitonin Autoimmune hepatitis, Primary biliary cirrhosis, Primary sclerosing cholangitis, Overlap syndrome Bacillus cereus sp., Food poisoning outbreak, Waterborne, Primary school. Histoplasmosis, Immunocompetent Hypoglycemia, Sheehan syndrome, Recurrent. Hypokalemic Quadriparesis, Dengue Fever Lipomatosis, Macroglossia, Madelung disease, Symmetrical lipomatosis. Metabolic syndrome, Epicardial fat, Echocardiography, Indian population. Pancytopenia, Panniculitis Peripheral arterial disease, Diabetes mellitus, Doppler ultrasound, Ankle-brachial index Progressive disseminated histoplasmosis, reversible CD4 depletion. Scrub typhus, Dengue, Thrombocytopenia Sebaceous gland carcinoma, Cryotherapy, Tubercular lymphadenitis Severe thrombocytosis, Iron deficiency anaemia, Chronic liver disease Sleep duration, Hulu Langat, younger age, smoking. Takayasu arteritis, cerebrovascular accident, infarction Thyroid, Menopause, Hypothyroidism, Prevalence Thyroid, Seizures, Encephalopathy Turmeric, Curcumin, Curcuma longa, Dentistry. Uveitis, Triamcenolone acetonide, Sub-Tenon’s injection, Ptosis, Glaucoma, Cataract extrahepatic manifestations and heaptitis c

About The Authors

Dr. Dinesh K Dhanwal
Dr. Dinesh K Dhanwal DM (AIIMS) Commonwealth Fellow, UK 2009-10 Director Prof. of Medicine and Endocrinologist Maulana Azad Medical College New Delhi
India

CURRICULUM VITAE

Name

Dr. Dinesh Kumar Dhanwal MBBS, MD, DM

Commonwealth Fellow 2009-10, University of Southampton

Date of Birth

01.01.1966

Official Address

Professor of Medicine and Endocrinologist,

Maulana Azad Medical College, New Delhi

Ph.91-11-23232400 Ext.4451, 25086502® 9968604275

Fax.91-11-23235793,

E-mail: dineshdhanwal@hotmail.com

PROFESSIONAL EXPERIENCE:

Oct 2008 onwards

Commonwealth Fellowship

September 2006-Oct 2008

Director Professor of Medicine and Endocrinologist

Commonwealth Fellow 2009-10, University of Southampton

Prof. Of Medicine and Division of Endocrinology

Maulana Azad Medical College,

Bahadur Shah ZafarMarg

New Delhi 110049

July 2004-August 2006

(Foreign Assignment)

Consultant Endocrinology

Zulekha Hospital

Sharjah and Dubai, UAE

Jan. 2000-Jan.2003

DM in service candidate, Dept. Of Endocrinology, All India Institute of Medical Sciences (AIIMS), New Delhi. Completed D.M. degree in December 2002.

June1996-Dec.-1999

Associate Professor of Medicine

Maulana Azad Medical College

New DELHI

June1994–June 1996

Assistant Professor of Medicine

JIPMER, Pondicherry

RESEARCH EXPERIENCE

Editor Medical Progress (Indian Edition)

Editorial board of Indian Journal of Endocrinology and Metabolism

Editor Scientific Proceedings Medicine Update 2006 and 2010

Reviewer for National and International jornals notably, Osteoporosis International and JCEM

Research Papers

VK Bahl, OP Malhotra, D Kumar, R AGARWAL, KC Goswami, R Bjaj and S Srivastva. Noninvasive assessment of systolic and diastolic left ventricular function in patients with chronic severe anemia: A combined M-mode, 2-dimension, Doppler echo study. Am Heart J.1992; 124:1516.
Dhanwal DK, Das AK. Spastic Para paresis in alcoholic cirrhosis with portal systemic encephalopathy. J Assoc Physicians India 1998; 46:400.
Dhanwal DK, Das AK. Hypopituitarism following snakebite. J Assoc Physicians India 1998; 46:322.
Rishi Sukhija, Dinesh Dhanwal, DS Gambhir, R Dewan. Silent Myocardial Ischemia in patients with type 2 DM and its’ correlation with autonomic function tests. Ind Heart J. 2000; 52:540-546.
Dinesh Dhanwal, Nikhil Tandon. Isolated menarche and multicystic ovaries in a seven and a half year girl. IndPed. 2001; 38; 432-433.
BenuDhawan, SrujanaMohanty, AC Ammini, Dhanwal, BK Das and ArtiKapil. Streptococcal Toxic Shock Syndrome. J Assoc Physicians India 2002; 50:599-600.
Kumar R, Sanjay Sharma, A Marwah, D Dhanwal and A Malhotra. Ectopic goiter masquerading as submandibular gland – A case report and review of literature. ClinNuc Med 2001; 26:306-309.
NP Singh, S Anuradha, DK Dhanwal, Kirti Singh, A Prakash, K Madan and SK Agarwal. Epidemic Dropsy- A clinical study of Delhi outbreak. J Assoc Physicians India. 2000; 48: 877-880.
Dinesh Dhanwal and Nikhil Tandon. Micro vascular complications in postprandial hyperglycemia. J Assoc Physicians India 2001; 49(Suppl 1).
Dhanwal D, Tandon N, Tandon R, Chumber S, Maher L, Ammini AC. Multiple Endocrine Neoplasia (MEN) Syndrome – 2B with Ectopic Cushing’ Syndrome. Accepted for publication in Endocrinologist.

11. Dhanwal DK, Sharma GRK, Das AK, Agarwal A. Acute lymphoblastic leukemia associated with Acute GullianeBarre Syndrome- a paraneoplastic syndrome! Antiseptic 1996; 8:306-7.

12. Dinesh Dhanwal, Ambuj Roy. Diabetic foot. Journal of DDF 1999; 2:12.

13. Dinesh Dhanwal, MukhopadhyaySurbhi. Gestational DM. ObsGynae Today 1999.

14. Dinesh Dhanwal. Jaundice in Pregnancy.Obs and Gynae Today.1999.

15. Ashraf GN, GhulamNabi, Tanon N, Manpreet G and Dhanwal DK. Mayor-Rokitansk-Kuster-Hauser Syndrome with presacral kidney: an unusual association. Urology 59: 000-000,2002.

16. Rastogi et al. (As participating physician in multicenter study). Diet and risk of coronary heart disease in India.Int J of Epidemiology 2004:33(4);759-767.

17. Rastogi et al. (As participating physician in multicenter project). Diet and risk of ischemic heart disease in India. 2004:77;582-592

18. Dinesh K Dhanwal. Bone Mineral Metabolism in Thyrotoxicosis. Ind J Endoc Met 2007;11(1,2):33-36.

19. .Dinesh K Dhanwal.Benefits of Medical therapy in large prolacinoma.Ind J Endoc Met 2007;11(1,2):61.

20. Dinesh K Dhanwal and R. Goswami. Lactic Acidosis. A chapter in Manual of Medical Therapeutics. 2008

21. Dinesh Dhanwal and AK Sharma. Brain and optic chiasm herniation following medical therapy in a patient with giant prolactinoma.Pituitary. 2009 Apr 19. [Epub ahead of print]

22. DPP-4 Inhibitors: a new paradigm in managing diabetes mellitus; a review. IJEM 2008: 12(8); 27-42.

24. Dhanwal Dinesh Kumar. Co morbidities and mortality in obesity. JIMSA 2008:21;141.

25. Dhanwal DK, Tandon N, Tandon R et al. Multiple Endocrine Neoplasia (MEN) syndrome-2B with ectopic Cushing Syndrome. The Endocrinologist; 2010:20;13-14.

26. Dinesh K Dhanwal. Oral Hypoglycemic Agents in 21st Century : A critical appraisal. JIMSA 2009:22;183-187.

27. Dhanwal DK, Dennison EM, Harvey NC, Cooper C. Epidemiology of hip fracture: Worldwide geographic variation.Indian J Orthop. 2011 Jan;45(1):15-22.

28. Dhanwal DK, Cooper C, Dennison EM. Geographic variation in osteoporotic hip fracture incidence: the growing importance of asian influences in coming decades. J Osteoporos. 2010 Aug 2;2010:757102.

29. Dhanwal DK. Oncogenic osteomalacia: A reversible metabolic bone disorder.Indian J Orthop. 2010 Oct;44(4):361-2.

30.Dhanwal DK, Kochupillai N, Gupta N, Cooper C, Dennison EM. Hypovitaminosis D and bone mineral metabolism and bone density in hyperthyroidism. J ClinDensitom. 2010 Oct-Dec;13(4):462-6. Epub 2010 Jul 21.

31. Dhanwal DK, Vyas A, Sharma A, Saxena A. Hypothalamic pituitary abnormalities in tubercular meningitis at the time of diagnosis. Pituitary. 2010 Dec;13(4):304-10.

32. Dhanwal DK, Gupta N. Trends of bone mineral density in patients with thyrotoxicosis after medical therapy. J Assoc Physicians India.2011; 59:562-67.

32. Dhanwal DK, Vyas A. GHD and hypothyroidism: a rare case. In Novo Nordisk news letter 2009.

33. Dinesh K. Dhanwal, Sanjay Kumar, Annirudha Vyas, Alpana Saxena1 Hypothalamic pituitary dysfunction in acute nonmycobacterial infections of central nervous system. Ind J Endo Met 2011;15:S233-37.

34. Kalra S, Dhanwal D, Khadilkar V. Hypopituitarism in tropics. Ind J Endo Met 2011;15:S151-153.

35. Dhanwal DK.. Thyroid disorders and bone mineral metabolism. Ind J Endo Met 2011;15:S107-12.

36. Simi Ratan, Dhanwal DK. Hypospadias and endocrine abnormalities accepted for publication

37. Screening of pregnant women for hypothyroidism during first trimester accepted in IJEM 2013

38. Microvascular complications in DM ESI book chapter

39. Epidemiology and risk factors for osteoporosis a book chapter in ESI book

40. Premkumar M, Sable T, Dhanwal D, Dewan R. Vitamin D homeostasis, bone mineral metabolism, and seasonal affective disorder during 1year of Antarctic residence. Arch Osteoporos. 2013 Dec;8(1-2):129. doi: 10.1007/s11657-013-0129-0. Epub 2013 Mar 9.

41. Dennison EM, Dhanwal DK, Shaheen SO, Azagra R, Reading I, Jameson KA, Sayer AA, Cooper C. Is lung function associated with bone mineral density? Results from the Hertfordshire Cohort Study. Arch Osteoporos. 2013 Dec;8(1-2):115.

42. Dhanwal DK. Vitamin D deficiency in hyperthyroidism. Indian J Med Res. 2012 Aug;136(2):311; author reply 311. No abstract available.

43. Dhanwal DK, Sahoo S, Gautam VK, Saha R. Hip fracture patients in India have vitamin D deficiency and secondary hyperparathyroidism.

Osteoporos Int. 2013 Feb;24(2):553-7.

44. Harvey N, Dhanwal D, Robinson S, Kim M, Inskip H, Godfrey K, Dennison E, Calder P, Cooper C; SWS Study Group.Does maternal long chain polyunsaturated fatty acid status in pregnancy influence the bone health of children? The Southampton Women's Survey.Osteoporos Int. 2012 Sep;23(9):2359-67

45. Dhanwal DK, Siwach R, Dixit V, Mithal A, Jameson K, Cooper C. Incidence of hip fracture in Rohtak district, North India.ArchOsteoporos. 2013 Dec;8(1-2):135. doi: 10.1007/s11657-013-0135-2. Epub 2013 Apr 26.

Abstracts in Indexed Journals

Dinesh Dhanwal , Abdul Hamide, J george, AK Das. Neurological manifestations in HIV disease- JIPMER experience. J Assoc Physicians India1996; 44:914.
Dhanwal DK. Dewan R, Gupta S, Chaturvedi Uma K,Bhattacharyaj,SarinS.Association of Helicobactor pylori infection with coronary heart disease in young. J Assoc Physicians Indaia.1998; 46:21.
Rohtagi A, Dhanwal DK, Gupta A, Sarin S, Dewan R. Lymphocytic colits-a diagnostic and therapeutic challenge. J Assoc Physicians India 1998; 46:80.
Dhanwal DK, Das AK, AgarwalAparna. Viral myocarditis mimicking acute myocardial infarction. J Assoc PHYSICIANS India.1998; 46:101.
Dewan R, Dhanwal DK, Rohtagi, Gupta R. Inferior vena cava thrombosis: an unusual presentation of tuberculosis. J Assoc Physicians India 1998; 46:119.
Dhanwal DK, Kumar R, Anil Pandey, AK Padhy, GS pant, AC Ammini. Influence of lithium on treatment for Grave’s Disease. Jap J Nucl Med 2001.
Roy A, Dhanwal DK, R Dewan, R Kohli, SNA Rizvi. Study of diurnal blood pressure variation in hypertension associated with end stage renal disease. J Assoc Physicians India1999; 47:128.
R Dewan, A Gupta, A Saxena, R Nehru, R Gupta, Dhanwal DK. Carbonmonooxide and lead poisoning following exposure to vehicular exhaust fumes. J Assoc Physicians India1999; 47:62.
Dhanwal DK, Kumar P, Nehru R. Profile of patients with diabetic foot from North India. Paper accepted during IDF 2003 in Paris.
Dhanwal DK, Gupta N, Kochupillai N, Bone mineral homeostasis and density in vitaminD deficient and sufficient patients with hyperthyroidism. Osteoporosis International 2008 Supp 1; 1- 22.
Dhanwal DK, Gupta N, Kochupillai N, Bone mineral homeostasis and density in Indian patients with hyperthyroidism. ANZBMS as abstract 2008: 79
Dhanwal DineshKumar et al. Recovery of bone mineral density in patients with hyperthyroidism after carbimazole therapy. Osteoporosis Interantional 2009 Supplement
IN 2010 three in OI Supplement
In 2011 two in OI supplement and one in ESI
In 2012 two in OI Supplement and others to follow
Dhanwal DK, Kataria B, Kumar V. Capture the fracture; a New Delhi initiative on secondary fracture preventionOsteoporosInt 2013 Supplement OC 45
Dhanwal DK, Dharamshaktu P, Sahoo S, Kumar S. Physical impairement and one year mortality of hip fracture in India. OsteoporosInt 2013 Supplement OC 20
And many more

D.M. (Endocrinology) Thesis

Bone mineral metabolism and bone density in vitamin D deficiency and sufficient patients with hyperthyroidism.
Carbimazole therapy and reversibility of bone loss in patients with hyperthyroidism.

Awards

1.Young Investigator award during 2001 and 2004 Japanese Society of Nuclear Medicine at Kanazawa and Quoto, Japan

2.Fellowship award during APPES meeting at Cairns Australia 2002.

3. AV Gandhi Award for Excellence in Endocrinologist Bangalore 2003

4. Fellow of Indian College of Physician (FICP) 2009

5. Commonwealth Academic Fellowship Award from Commonwealth Commission, UK in 2009-10

6. American Society of Bone Mineral Research travel grant award 2010

7. Guide for Young investigator award from International Osteoporosis Foundation to DrSarojSahoo in Singapore 2010

8. Guide for Young investigator award from International Osteoporosis Foundation to DrMandal in Gold Coast, Australia 2011

9. 27^th Dr. S. Radha Krishnan Memorial National Teachers award 2011

Vivek Dixit
Dr Vivek Dixit Postdoctoral Fellow Endocrinology and Metabolism Hadassah-Hebrew University Medical Center POB 12000, Jerusalem 91120, Israel
Israel

Endocrinology and Metabolism

R K Marwah
INMAS, Delhi
India

Consultant, Head of INMAS

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Journal of Advanced Research in Medicine (P-ISSN:2394-7047 & E-ISSN:2349-7181)

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