Prevalence of Vitamin D Deficiency in Coronary Artery Disease Diabetic and Non Coronary Artery Disease Diabetic Patients in Northern India

Abstract

Introduction: Vitamin D deficiency is prevalent across the globe. Its supplementation at an early stage may prevent several diseases related to it.

Aim: To find out the prevalence of Vitamin D deficiency in CAD diabetic and Non CAD diabetic patients in Northern India.

Materials and Methods: The proposed study included 200 patients with age 50 years and above. These patients were equally divided into two groups CAD diabetic (N=100) and Non CAD diabetic (N=100) on the basis of clinical features, assessment, laboratory parameters and medical history. CAD was diagnosed on the basis of history and with criteria of low Ejection Fraction (≤45) and angiography result. Vitamin D level in all these patients was measured and was correlated with HbA1c values and other biochemical parameters. Data was analyzed using ANOVA and T test.

Results: Vitamin D levels were on the lower side in the CAD diabetic group (12.69 ± 6.30) than in Non CAD diabetic group (15.98 ± 7.24). Out of the 200 patients investigated Vitamin D deficiency was observed in 89 patients in the CAD diabetic group (N=100) and the same was only 83 in the Non CAD diabetic group (N=100). Mean HbA1c in CAD diabetic (8.34 ± 1.14) and Non CAD diabetic (8.19 ± .94) was almost similar in both the groups.

Conclusion: We reported severe Vitamin D deficiency in CAD diabetic patients when it was compared with the Non CAD diabetic group. There was no significant difference between HbA1c values in both the groups.